Olga Abián Selected Research

Inosine Diphosphate (IDP)

10/2021	Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.
11/2019	Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.
1/2019	Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
1/2018	Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1).
1/2017	Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma.

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Olga Abián Research Topics

Disease

4	Neoplasms (Cancer) 10/2021 - 01/2019
3	Adenocarcinoma 11/2019 - 01/2017
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019
1	Infections 01/2011

Drug/Important Bio-Agent (IBA)

5	Inosine Diphosphate (IDP)IBA 10/2021 - 01/2017
5	Intrinsically Disordered ProteinsIBA 10/2021 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 10/2021 - 11/2019
3	NUPR1 inhibitor ZZW-115IBA 01/2020 - 01/2019
2	Pharmaceutical PreparationsIBA 10/2021 - 01/2019
1	Biological ProductsIBA 10/2021
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2020
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2020
1	Antipsychotic Agents (Antipsychotics)IBA 01/2019
1	Trifluoperazine (Stelazine)FDA LinkGeneric 01/2019
1	ChromatinIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2011